Advanced skin care of Skin types III-VI may require the use of skin lightening and depigmenting agents. The limelight facial may be used to treat pigmented lesions, to remove the melanin from the epidermis. This may be more easily accomplished with the use of depigmenting agents such as tyrosinase inhibitors.
Skin Lightening and Depigmenting Agents
Depigmenting agents are commonly prescribed to treat disorders of hyperpigmentation.
A basic understanding of the pigmentation pathway is helpful prior to a discussion of various skin-lightening agents and their known mechanisms of action. The type and amount of melanin synthesized by the melanocyte and its distribution pattern in the epidermis determines the actual color of the skin. Melanin forms through a series of oxidative reactions involving the amino acid tyrosine and the enzyme tyrosinase.
"Skin Lightening and Depigmenting Agents"
Author: Alaina J James, MD, PhD, Staff Physician, Department of Dermatology, University of Pennsylvania Medical Center
Coauthor(s): Cherie M Ditre, MD, Assistant Professor, Director, Cosmetic Dermatology and The Skin Enhancement Center, Department of Dermatology, Penn Medicine at Radnor, University of Pennsylvania School of Medicine; P Michael Tabibian, MD, Consulting Staff, Department of Dermatology, Daniel Freedman Hospital, Marina Hospital
Skin Lightening and Depigmenting Agents
Depigmenting agents are commonly prescribed to treat disorders of hyperpigmentation.
A basic understanding of the pigmentation pathway is helpful prior to a discussion of various skin-lightening agents and their known mechanisms of action. The type and amount of melanin synthesized by the melanocyte and its distribution pattern in the epidermis determines the actual color of the skin. Melanin forms through a series of oxidative reactions involving the amino acid tyrosine and the enzyme tyrosinase.
"Skin Lightening and Depigmenting Agents"
Author: Alaina J James, MD, PhD, Staff Physician, Department of Dermatology, University of Pennsylvania Medical Center
Coauthor(s): Cherie M Ditre, MD, Assistant Professor, Director, Cosmetic Dermatology and The Skin Enhancement Center, Department of Dermatology, Penn Medicine at Radnor, University of Pennsylvania School of Medicine; P Michael Tabibian, MD, Consulting Staff, Department of Dermatology, Daniel Freedman Hospital, Marina Hospital
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